|
Hour
|
Category*
|
Control
|
25 mM Furfural
|
50 mM Furfural
|
|---|
|
6
|
Tubular
|
80 ± 13
|
50 ± 5
|
10 ± 2
|
|
6
|
Fragmented
|
19 ± 13
|
41 ± 2
|
45 ± 3
|
|
6
|
Aggregated
|
1 ± 0.4
|
9 ± 2
|
45 ± 2
|
|
24
|
Tubular
|
94 ± 4
|
27 ± 8
|
4 ± 4
|
|
24
|
Fragmented
|
6 ± 2
|
49 ± 4
|
33 ± 23
|
|
24
|
Aggregated
|
< 1 ± 1
|
24 ± 10
|
66 ± 28
|
|
48
|
Tubular
|
17 ± 5
|
16 ± 10
|
0
|
|
48
|
Fragmented
|
79 ± 3
|
53 ± 15
|
0
|
|
48
|
Aggregated
|
4 ± 2
|
31 ± 6
|
100 ± 0
|
- Prior to adding furfural, 87%, 12% and 1% of cells contained tubular, fragmented and aggregated mitochondria, respectively. Data represent averages of three experiments with standard error indicated. At least 100 cells were examined at each time point.
- * Tubular mitochondria are a network of evenly distributed tubules that are often connected; fragmented mitochondria are small evenly distributed spherical structures; aggregated mitochondria are small and clustered spherical structures that are not evenly distributed.
