TY - JOUR AU - Ilmén, Marja AU - den Haan, Riaan AU - Brevnova, Elena AU - McBride, John AU - Wiswall, Erin AU - Froehlich, Allan AU - Koivula, Anu AU - Voutilainen, Sanni P. AU - Siika-aho, Matti AU - la Grange, Daniël C. AU - Thorngren, Naomi AU - Ahlgren, Simon AU - Mellon, Mark AU - Deleault, Kristen AU - Rajgarhia, Vineet AU - van Zyl, Willem H. AU - Penttilä, Merja PY - 2011 DA - 2011/09/12 TI - High level secretion of cellobiohydrolases by Saccharomyces cerevisiae JO - Biotechnology for Biofuels SP - 30 VL - 4 IS - 1 AB - The main technological impediment to widespread utilization of lignocellulose for the production of fuels and chemicals is the lack of low-cost technologies to overcome its recalcitrance. Organisms that hydrolyze lignocellulose and produce a valuable product such as ethanol at a high rate and titer could significantly reduce the costs of biomass conversion technologies, and will allow separate conversion steps to be combined in a consolidated bioprocess (CBP). Development of Saccharomyces cerevisiae for CBP requires the high level secretion of cellulases, particularly cellobiohydrolases. SN - 1754-6834 UR - https://doi.org/10.1186/1754-6834-4-30 DO - 10.1186/1754-6834-4-30 ID - Ilmén2011 ER -