Effect of organic acids on the growth and lipid accumulation of oleaginous yeast Trichosporon fermentans

Table 2 Concentration of organic acids required to inhibit the lipid yield of Trichosporon fermentans

Organic acid	IC₂₅^a (mM)	Relative biomass (%)	Relative lipid content (%)	IC₅₀^b (mM)	Relative biomass (%)	Relative lipid content (%)	LogP^c
Formic acid	43.4	92	81	80.4	72	68	-0.54
Acetic acid	30.0	87	83	66.6	68	78	-0.17
Levulinic acid	146.4	90	82	310.0	79	61	-0.49
4-hydroxybenzoic acid	97.7	84	89	188.2	67	80	1.58
Vanillic acid	15.5	80	93	60.7	63	79	1.43
Syringic acid	9.6	79	94	78.2	58	86	1.04
Furoic acid	17.8	70	106	93.7	52	98	1.06
Gallic acid	67.6	88	86	135.2	63	74	0.7
Ferulic acid	3.1	76	99	7.7	51	97	1.51
Caproic acid	3.0	88	83	5.6	71	69	1.92

^aMolar concentration of 25% inhibition on lipid yield. ^bMolar concentration of 50% inhibition on lipid yield. ^cThe LogP data are from work by Zaldivar and Ingram [24].

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