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Figure 1 | Biotechnology for Biofuels

Figure 1

From: Cytosolic re-localization and optimization of valine synthesis and catabolism enables increased isobutanol production with the yeast Saccharomyces cerevisiae

Figure 1

Schematic illustration of the synthetic isobutanol biosynthesis pathway. Glucose is converted to pyruvate via glycolysis. Pyruvate can be further converted to 2-ketoisovalerate (KIV) in the cytosol by the re-localized Ilv2, Ilv5 and Ilv3 enzymes. KIV is metabolized into isobutanol via the Ehrlich pathway reactions catalyzed by Aro10 and Adh2. GAP = glyceraldehyde-3-phosphate; PYR = pyruvate; ALAC = 2-acetolactate; DIV = 2,3-dihydroxyisovalerate; IBA = isobutyraldehyde.

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Biotechnology for Biofuels and Bioproducts

ISSN: 2731-3654

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