Figure 5From: Microevolution from shock to adaptation revealed strategies improving ethanol tolerance and production in ThermoanaerobacterMolecular events underpinning development of ethanol tolerance in thermopiles. The transition from the shock response in X ( A ) to the low-tolerance in XI( B ) and eventually to the high-tolerance in XII( C ) was shown. Key transport, metabolic and regulatory genes and pathways were illustrated. Fla: flagellar biosynthesis; BTSs: binding-protein-dependent transport systems; Aldo: aldo/ketoreductase; PBD: peptidoglycan binding domain-containing protein; CcdA: cytochrome c biogenesis protein; TSPP: transport system permeaseprotein.PBP: periplasmic binding protein; IspC: cell wall hydrolase/autolysin; CPBP: capsule polysaccharide biosynthesis protein; PBDP: peptidoglycan binding domain-containing protein; FURF: ferric uptake regulator family protein; HP: hypothetical protein.Back to article page