Table 2 Important gene tragets induced by butanol
Gene ID | Butanol vs.Control at 24Â h | Butanol vs.Control at 48Â h | Butanol vs.Control at 72 h | Description |
|---|---|---|---|---|
Cell envelope | ||||
 sll0034 | 2.52 | 1.54 | 1.86 | D, D-carboxypeptidase |
 sll0286 | 2.33 | 1.90 | 1.55 | Uncharacterized N-acetyltransferase |
 sll0886 | 1.88 | 1.78 | 2.79 | UDP-N-acetylglucosamme-peptide N-acetylglucosammyltransferase- |
 sll1053 | 3.52 | 4.00 | 12.12 | Membrane fusion protein mtrc precursor, putative |
 sll1395 | 1.91 | 2.61 | 1.54 | dTDP-6--6-deoxy-L-mannose-dehydrogenase |
 sll2010 | 1.60 | 1.78 | 2.89 | UDP-N-acetylmuramoylalanine--D-glutamate ligase |
 slr0528 | 2.52 | 1.91 | 2.45 | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase |
 slr0993 | 1.75 | 2.33 | 4.21 | Putative peptidase |
 slr1166 | 2.86 | 1.68 | 2.36 | UDP-glucose:tetrahydrobiopterin glucosyltransferase |
 slr1196 | 4.07 | 1.91 | 2.74 | Periplasmic protein, function unknown |
 slr1744 | 1.89 | 1.92 | 2.42 | N-acetylmuramoyl-L-alanine amidase, periplasmic protein |
 slr2015 | 3.56 | 4.15 | 2.39 | Type 4 pilin-like protein, essential for motility |
 slr2016 | 4.40 | 1.71 | 1.71 | Type 4 pilin-like protein, essential for motility |
Central intermediary metabolism | ||||
 sll0646 | 4.03 | 1.87 | 1.96 | Guanylyl cyclase |
 slr0288 | 1.65 | 2.28 | 2.58 | Glutamate--ammonia ligase |
 slr0899 | 2.19 | 2.75 | 2.50 | Cyanate lyase |
 slr0940 | 3.33 | 1.96 | 4.21 | Zeta-carotene desaturase |
 slr1254 | 1.73 | 1.76 | 4.43 | Phytoene dehydrogenase (phytoene desaturase) |
 slr1877 | 6.00 | 3.15 | 3.75 | 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase |
Common stress response | ||||
 sll0248 | 3.60 | 3.67 | 1.86 | Flavodoxin |
 sll1388 | 3.21 | 1.58 | 1.82 | Universal stress protein |
 sll1988 | 1.90 | 1.53 | 1.81 | 33 kDa chaperonin |
 slr0093 | 2.61 | 1.53 | 2.61 | DnaJ protein, molecular chaperone |
 slr1795 | 2.43 | 1.71 | 2.16 | Peptide methionine sulfoxide reductase |
 slr1828 | 3.38 | 3.33 | 11.00 | Ferredoxin, petF-like protein |
 slr1846 | 1.53 | 2.25 | 4.71 | Uncharacterized monothiol glutaredoxin |
 slr1854 | 4.09 | 1.59 | 4.38 | General stress protein 18 (gsp17 ) |
 slr2047 | 2.06 | 1.65 | 1.62 | Phosphate starvation-inducible protein |
 ssl2250 | 6.00 | 2.00 | 5.00 | Bacterioferritin-associated ferredoxin |
Protein fate | ||||
 sll0616 | 4.19 | 1.88 | 3.54 | Preprotein translocase SecA subunit |
 sll0716 | 3.50 | 3.00 | 1.83 | Probable signal peptidase I-1 |
 slr0835 | 1.87 | 2.17 | 6.92 | MoxR protein homolog |
 slr0994 | 2.22 | 1.62 | 2.30 | Octanoyltransferase |
 slr1046 | 1.86 | 1.75 | 1.50 | Putative TatA protein |
 slr1204 | 4.18 | 2.63 | 5.57 | Putative serine protease HtrA |
 slr1331 | 2.94 | 2.26 | 3.98 | Periplasmic processing protease |
 ssr3307 | 1.76 | 1.63 | 2.04 | Preprotein translocase SecG subunit |
Regulatory functions | ||||
 sll0043 | 3.20 | 3.20 | 2.21 | Positive phototaxis histidine kinase |
 sll0690 | 5.00 | 1.57 | 6.00 | Probable transcription regulator |
 slr0640 | 2.28 | 1.86 | 2.20 | Two-component sensor histidine kinase |
 slr0780 | 1.84 | 1.70 | 2.33 | Transcriptional repressor NrdR |
 slr0947 | 3.18 | 2.38 | 5.44 | Response regulator for energy transfer from phycobilisomes to photosystems |
 slr1037 | 3.63 | 2.00 | 3.33 | Two-component response regulator CheY subfamily |
 slr1042 | 3.60 | 2.45 | 1.72 | Two-component response regulator CheY subfamily |
 slr1414 | 1.54 | 1.67 | 1.66 | Two-component sensor histidine kinase |
 slr1531 | 3.00 | 1.83 | 1.55 | Signal recognition particle protein |
 slr1805 | 1.53 | 3.81 | 4.66 | Two-component sensor histidine kinase |
 ssl0707 | 2.67 | 1.93 | 2.78 | Nitrogen regulatory protein P-II |
Storage compound biosynthesis | ||||
 slr1993 | 8.75 | 1.76 | 4.79 | PHA-specific beta-ketothiolase |
 slr1994 | 32.00 | 11.50 | 4.86 | PHA-specific acetoacetyl-CoA reductase |
 slr2002 | 3.52 | 2.09 | 2.57 | Cyanophycin synthetase |
Transport and binding proteins | ||||
 sll0374 | 1.65 | 1.90 | 2.83 | Urea transport system ATP-binding protein |
 sll0689 | 2.21 | 1.63 | 3.28 | Na+/H + antiporter |
 sll0759 | 3.11 | 1.56 | 6.87 | ABC transporter ATP-binding protein |
 sll1041 | 3.74 | 2.50 | 3.43 | Similar to sulfate transport ATP-binding protein CysA |
 sll1154 | 1.76 | 2.80 | 3.98 | NorA |
 sll1164 | 6.60 | 1.50 | 1.60 | Uncharacterized transporter |
 sll1428 | 32.00 | 2.00 | 7.00 | Probable sodium-dependent transporter |
 sll1450 | 2.89 | 3.98 | 5.27 | Nitrate/nitrite transport system substrate-binding protein |
 sll1451 | 2.52 | 1.73 | 5.97 | Nitrate/nitrite transport system permease protein |
 sll1452 | 1.98 | 1.66 | 3.12 | Nitrate/nitrite transport system ATP-binding protein |
 sll1481 | 3.14 | 1.66 | 3.38 | ABC-transporter membrane fusion protein |
 sll1482 | 3.30 | 1.51 | 2.57 | ABC transporter permease protein |
 sll1623 | 2.15 | 1.56 | 1.91 | ABC transporter ATP-binding protein |
 slr1248 | 2.57 | 2.63 | 3.00 | Phosphate transport system permease protein PstC homolog |
 slr1295 | 2.33 | 1.79 | 5.92 | Iron transport system substrate-binding protein |
 slr1318 | 1.50 | 2.50 | 1.77 | Iron (III) dicitrate transport system ATP-binding protein |
 slr1515 | 2.56 | 1.61 | 3.47 | Putative membrane protein required for bicarbonate uptake |
 slr1729 | 1.96 | 1.52 | 2.13 | Potassium-transporting P-type ATPase B chain |
 slr2131 | 4.50 | 2.51 | 12.87 | RND multidrug efflux transporter |