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Table 4 Experimental design and results of central composition experiment

From: A newly isolated Bacillus licheniformisstrain thermophilically produces 2,3-butanediol, a platform and fuel bio-chemical

Run

Coded variable level

2,3-BD (g/L)

X 1

X 2

X 3

Observed

Predicted

1

−1

−1

−1

32.2

32.2

2

1

−1

−1

35.0

35.0

3

−1

1

−1

34.0

34.9

4

1

1

−1

33.6

32.6

5

−1

−1

1

35.7

35.8

6

1

−1

1

41.0

39.2

7

−1

1

1

37.9

36.9

8

1

1

1

36.1

35.3

9

−1.682

0

0

36.2

35.8

10

1.682

0

0

35.2

36.8

11

0

−1.682

0

33.8

34.4

12

0

1.682

0

32.7

33.3

13

0

0

−1.682

34.5

34.1

14

0

0

1.682

37.7

39.3

15

0

0

0

41.3

41.8

16

0

0

0

43.0

41.8

17

0

0

0

40.7

41.8

18

0

0

0

42.7

41.8

19

0

0

0

41.6

41.8

20

0

0

0

41.8

41.8