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Table 4 Experimental design and results of central composition experiment

From: A newly isolated Bacillus licheniformisstrain thermophilically produces 2,3-butanediol, a platform and fuel bio-chemical

Run Coded variable level 2,3-BD (g/L)
X 1 X 2 X 3 Observed Predicted
1 −1 −1 −1 32.2 32.2
2 1 −1 −1 35.0 35.0
3 −1 1 −1 34.0 34.9
4 1 1 −1 33.6 32.6
5 −1 −1 1 35.7 35.8
6 1 −1 1 41.0 39.2
7 −1 1 1 37.9 36.9
8 1 1 1 36.1 35.3
9 −1.682 0 0 36.2 35.8
10 1.682 0 0 35.2 36.8
11 0 −1.682 0 33.8 34.4
12 0 1.682 0 32.7 33.3
13 0 0 −1.682 34.5 34.1
14 0 0 1.682 37.7 39.3
15 0 0 0 41.3 41.8
16 0 0 0 43.0 41.8
17 0 0 0 40.7 41.8
18 0 0 0 42.7 41.8
19 0 0 0 41.6 41.8
20 0 0 0 41.8 41.8