Statistically significant amino acids and intramolecular interactions between thermostable and mesostable endoglucanases. They are shown in thermostable endoglucanases as an enzyme group, based on the reaction mechanism, and within each fold, as compared to their mesostable counterparts (p-value < 5.0 × 10-2). The other interactions such as side chain-side chain interactions, hydrophobic interactions, disulphide bonds, and aromatic interactions were analyzed but found not to be statistically significant. The statistically significant intramolecular interactions for thermostable are shaded in dark gray. Note that the results for inverting mechanism and on (α/α)6 fold are the same. Figure reproduced with from a BioMed Central publication under the Creative Commons Attribution License from.