Table 1 Top ten scoring reporter metabolites connected to transcriptome changes after inhibitor pulse in the glucose consumption phase
Metabolite | Number of neighbors | Pvalue |
|---|---|---|
Reporter metabolites (up) | ||
Glutathione [c] | 10 | 6.0E-05 |
UDP-glucose [c] | 11 | 3.1E-04 |
D-galactose [e] | 6 | 2.5E-03 |
Alpha,alpha-trehalose 6-phosphate [c] | 4 | 3.7E-03 |
Alpha,alpha-trehalose [c] | 4 | 6.0E-03 |
Alpha-D-glucose 6-phosphate [c] | 8 | 8.2E-03 |
Oxidized glutathione [c] | 4 | 6.6E-03 |
CDP-diacylglycerol [m] | 4 | 8.6E-03 |
Alpha-D-glucose [c] | 23 | 2.2E-02 |
D-glucose 1-phosphate [c] | 6 | 1.2E-02 |
Reporter metabolites (down) | ||
AMP [c] | 42 | 5.4E-09 |
ATP [c] | 83 | 1.1E-08 |
5-phospho-alpha-D-ribose 1-diphosphate [c] | 15 | 2.5E-06 |
L-glutamine [c] | 17 | 6.6E-06 |
L-histidine [c] | 7 | 8.2E-05 |
L-aspartate [c] | 12 | 8.7E-05 |
CO2 [m] | 10 | 1.3E-04 |
Isocitrate[m] | 5 | 2.5E-04 |
Phosphate [c] | 49 | 8.5E-05 |
Glycine [m] | 4 | 9.6E-04 |