Figure 2

CCR-regulation of cellulose degradome components in C. cellulolyticum . (A) Expression profiles of CAZymes under the selected carbon sources (glucose (Glu), cellobiose (Ceb), xylose (Xyl), cellulose (Cel), xylan (Xyn) and corn stover (CS)) were clustered into four groups by hierarchical clustering analysis and gene function. The structural (cellulosomal component (CC) and noncellulosomal enzyme (NC)) and functional (glycoside hydrolase (GH), glycosyltransferase (GT), carbohydrate esterase (CE), polysaccharide lyase (PL), cellulosomal noncatalytic subunit (CN) and unknown function enzyme (UF)) characteristics of CAZmes were distinguished by different color-blocks. (B) The expression correlation of the 50 cellulosomal genes under various carbon sources. Correlation coefficients (R²) were calculated (n = 50) for all cellulosomal genes except the “xyl-doc” cluster. The arrows indicated the order in average transcript abundance (from low to high) of the genes under the different conditions. (C) Correlation of NTA between “cip-cel” cluster and lfpC2-IfpC3 (Ccel_2999 -3000) under different carbon sources.