Figure 4

Protein kinase A was hyperactivated upon growth on AVICEL or carbon starvation. The parental (WT), ∆pkaC and ∆cyaA strain were grown in minimal media plus 1% fructose overnight (o/n) and then transferred to various alternative carbon sources for 8 h. The PKA activity from the respective cultures, and the internal cAMP (positive) and water (negative) controls, were determine via densitometry. One-tailed t-test (* P <0.05, ** P < 0.01, *** P < 0.001).