Table 1 MIPS functional classification of genes differentially regulated by both C9 and C10

Up-regulated

fatty acid metabolism

5

24

phospholipid metabolism

7

68

oxidative stress response

6

55

tetracyclic and pentacyclic triterpenes

5

36

cellular import

7

90

lipid/fatty acid transport

5

44

ABC transporters

4

28

lipid, fatty acid and isoprenoid metabolism

8

133

degradation of glutamate

2

4

metabolism of amino acid-derived secondary products

2

4

NAD/NADP binding

4

36

C-compound and carbohydrate metabolism

10

223

heat shock response

3

20

chemical agent resistance

3

22

S-adenosyl-methionine-homocysteine cycle

2

7

pH stress response

2

8

oxidation of fatty acids

2

9

transport ATPases

4

53

Down-regulated

biosynthesis of thiamine

6

110

transport facilities

5

87

degradation of lysine

2

5

degradation of glycine

2

6

transport routes

2

11

metabolism of thiamine

3

43

tetrahydrofolate-dependent C-1-transfer

2

13