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Table 2 Gene ontology analysis of transcriptional responses of CTY and INVSc1 hosts to xylose metabolism

From: Investigating host dependence of xylose utilization in recombinant Saccharomyces cerevisiae strains using RNA-seq analysis

GO ID

Description

CW vs CC

CW vs CI

IW vs IC

IW vs II

Up-regulated

GO:0000902

cell morphogenesis

FKS1

   

GO:0005975

carbohydrate metabolic process

ERR1, FKS1, GPH1, GPM1, IMA1, MAL12, PYK2, SUC2, CIT1

ALG13, ALG2, CIT1, CWH41, GPH1, KRE6, PYC1, STT3

  

GO:0006091

generation of precursor metabolites and energy

ATF1, ERR1, FRE3, GPH1, GPM1, PYK2, CIT1

CIT1, GPH1, OLE1

  

GO:0006457

protein folding

 

CPR7

  

GO:0006486

protein glycosylation

 

ALG2, CWH41, STT3

  

GO:0006520

cellular amino acid metabolic process

GDH1, CIT1

ASN1, CIT1, GDH3, LEU1, MET13, MET16, TRP5, YGR012W

  

GO:0006629

lipid metabolic process

MCR1, YPC1

ALG13, ALG2, ECT1, ERG26, ERG4, MET13, MET16, OLE1, POX1

  

GO:0006811

ion transport

FRE3

   

GO:0006873

cellular ion homeostasis

FRE3

   

GO:0006897

endocytosis

FKS1

   

GO:0006979

response to oxidative stress

AHP1, MCR1

   

GO:0008033

tRNA processing

 

PUS2

  

GO:0008380

RNA splicing

MNE1

   

GO:0009311

oligosaccharide metabolic process

IMA1, MAL12, SUC2

ALG2, CWH41

  

GO:0009451

RNA modification

 

PUS2

  

GO:0018193

peptidyl-amino acid modification

 

CPR7

  

GO:0023052

signaling

PDE2

   

GO:0042221

response to chemical stimulus

AHP1, MCR1

MNL1

  

GO:0045333

cellular respiration

CIT1

CIT1

  

GO:0051049

regulation of transport

FKS1

   

GO:0051603

proteolysis involved in cellular protein catabolic process

 

ATE1, MNL1

  

GO:0051604

protein maturation

 

KEX1

  

GO:0051186

cofactor metabolic process

ACH1, ALD4, FDH1, CIT1

CIT1, HEM2, MET13, NMA2, NPY1, PNC1, PYC1

  

GO:0055086

nucleobase-containing small molecule metabolic process

ALD4, FDH1

NMA2, NPY1, PNC1, PYC1

  

GO:0071554

cell wall organization or biogenesis

 

CWH41, KRE6

  

Un-identified, up-regulated genes*

POT1, SDH1

BAT1

  

Down-regulated

GO:0005975

carbohydrate metabolic process

CIT3

  

RPE1

GO:0006091

generation of precursor metabolites and energy

CIT3

   

GO:0006470

protein dephosphorylation

  

YMR1

 

GO:0006520

cellular amino acid metabolic process

 

GSH2

CPA2, URA8

URA2

GO:0006605

protein targeting

ACC1

   

GO:0006629

lipid metabolic process

ACC1, ARE2, CIT3, LRO1

 

URA8, YJR107W, YMR1

LCB3

GO:0006873

cellular ion homeostasis

  

SOD1

 

GO:0006979

response to oxidative stress

  

SOD1

 

GO:0006997

nucleus organization

ACC1

   

GO:0023052

signaling

   

LCB3

GO:0042221

response to chemical stimulus

  

SOD1

 

GO:0045333

cellular respiration

CIT3

   

GO:0051169

nuclear transport

ACC1

   

GO:0051186

cofactor metabolic process

ACC1, CIT3

  

RPE1

GO:0055086

nucleobase-containing small molecule metabolic process

ACC1, URK1

 

ADO1, URA8

RPE1, URA2

GO:0071554

cell wall organization or biogenesis

  

SOD1

 

Un-identified, down-regulated genes*

NIT2

Summary

Up-regulated

22

30

0

0

Down-regulated

5

1

6

4

  1. Note: the genes marked as bold and italic have over 10 fold changes of expression, while the others have less than 10 fold changes of expression.
  2. *: some of the genes that were down-/up- regulated cannot be mapped into GO slim files.