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Table 1 Hydrophobicity values (logP octanol/water coefficients), millimolar inhibitory concentrations (IC 25 , IC 50 , IC 75 and IC 100 ) for growth rate inhibitions by 25%, 50%, 75% and 100%, respectively in glucose and xylose

From: Inhibition of growth of Zymomonas mobilis by model compounds found in lignocellulosic hydrolysates

  

RMG

RMX

Compound

Hydrophobicity (logPoctanol/water)

IC25

IC50

IC75

IC100

IC25

IC50

IC75

IC100

Organic acids 9

         

Oxalic acid

-2.20 1

33

53

71

90

29

59

86

105

Lactic acid

-0.60 3

210

315

415

600

100

170

265

400

Succinic acid

-0.59 2

165

210

260

340

165

195

260

340

Formic acid

-0.54 2

50

85

130

240

14

23

35

65

Levulinc acid

-0.49 5

130

220

300

475

35

50

65

90

Acetic acid

-0.17 2

140

210

280

360

25

50

70

110

2-Furoic acid

0.64-0.73 3

85

145

215

300

30

60

100

180

Itaconic acid

0.71 1

150

185

220

320

185

220

250

385

Vanillic acid 10

1.43 4

33

70

105

145

27

40

55

74

Ferulic acid

1.51 6

40

65

90

120

35

55

90

120

4-Hydroxybenzoic acid 10

1.58 6

35

75

105

145

25

40

55

90

4-Hydroxycinnamic acid 11 (ρ-Coumaric acid)

1.79 7

30

55

80

105

21

34

47

61

Benzoic acid

1.87 2

25

55

75

125

8

9

18

33

Caproic (Hexanoic) acid

1.92 2

7

12

18

34

3

5

9

17

Inorganic acids 9

         

Hydrochloric acid

 

215

260

305

400

250

305

355

400

Sulfuric acid

 

150

180

205

300

230

255

275

300

Phosphoric acid

 

190

240

285

330

340

375

400

460

Nitric acid

 

115

155

190

250

105

150

185

210

Aldehydes

         

HMF

-0.37 8

10*

22*

37*

63*

12

26

42

63

Furfural

0.41 2

8*

17*

27*

52*

9

16

26

42

Syringaldehyde 11

0.99 8

11

18

26

40

5

10

14

28

Vanillin

1.21 2

2

4

9

20

1

3

5

13

4-Hydroxybenzaldehyde

1.35 5

2

5

10

25

3

7

12

25

Alcohols

         

Furfuryl alcohol

0.28 2

60

100

140

220

60

100

140

205

Ethanol

-0.24 2

910*

1350*

1735*

2170*

950

1260

1600

2170

  1. 1 Estimated Values from Yaws’ Handbook of Thermodynamic and Physical Properties of Chemical Compounds © 2003 Knovel, Table: Solubility in Water and Octanol-Water Partition Coefficient.
  2. 2 Measured Values from Yaws’ Handbook of Thermodynamic and Physical Properties of Chemical Compounds © 2003 Knovel, Table: Solubility in Water and Octanol-Water Partition Coefficient.
  3. 3 Handbook of Environmental Data on Organic Chemicals (4th Edition) © 2001 John Wiley & Sons; Table: Physical and Environmental Data on Organic Chemicals (2-Furoic Acid is calculated).
  4. 4 Perry’s Chemical Engineers’ Handbook (7th Edition) © 1997 McGraw-HillChemicals; Table: Safety Properties of Common Solvents.
  5. 5 Chemical Properties Handbook © 1999 McGraw-Hill; Table:
  6. 6 Exploring QSAR,Hydrophobic, Electronic, and Steric Constants Hansch C, Leo A, and Hoekman D 1995 Amer. Chem. Soc., Washington DC.
  7. 7 Octanol-Water Partition Coefficients: Fundamentals and Physical Chemistry. Sangster J 1994 Wiley, New York.
  8. 8 Partition coefficients calculated from Biobyte, Inc. (Clarement, CA), cited [1618].
  9. 9 Inhibitory concentrations (IC) obtained for the NH4+ cation of the acids, except for oxalic acid in which case, K+ was used).
  10. 10 Inhibitory concentrations in bold were extrapolated from the inhibition curve.
  11. 11 Indicated compounds were dissolved in DMSO (< 5% (v/v)) because of low solubilities.
  12. * Reported [22].