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Table 1 Hydrophobicity values (logP octanol/water coefficients), millimolar inhibitory concentrations (IC 25 , IC 50 , IC 75 and IC 100 ) for growth rate inhibitions by 25%, 50%, 75% and 100%, respectively in glucose and xylose

From: Inhibition of growth of Zymomonas mobilis by model compounds found in lignocellulosic hydrolysates

   RMG RMX
Compound Hydrophobicity (logPoctanol/water) IC25 IC50 IC75 IC100 IC25 IC50 IC75 IC100
Organic acids 9          
Oxalic acid -2.20 1 33 53 71 90 29 59 86 105
Lactic acid -0.60 3 210 315 415 600 100 170 265 400
Succinic acid -0.59 2 165 210 260 340 165 195 260 340
Formic acid -0.54 2 50 85 130 240 14 23 35 65
Levulinc acid -0.49 5 130 220 300 475 35 50 65 90
Acetic acid -0.17 2 140 210 280 360 25 50 70 110
2-Furoic acid 0.64-0.73 3 85 145 215 300 30 60 100 180
Itaconic acid 0.71 1 150 185 220 320 185 220 250 385
Vanillic acid 10 1.43 4 33 70 105 145 27 40 55 74
Ferulic acid 1.51 6 40 65 90 120 35 55 90 120
4-Hydroxybenzoic acid 10 1.58 6 35 75 105 145 25 40 55 90
4-Hydroxycinnamic acid 11 (ρ-Coumaric acid) 1.79 7 30 55 80 105 21 34 47 61
Benzoic acid 1.87 2 25 55 75 125 8 9 18 33
Caproic (Hexanoic) acid 1.92 2 7 12 18 34 3 5 9 17
Inorganic acids 9          
Hydrochloric acid   215 260 305 400 250 305 355 400
Sulfuric acid   150 180 205 300 230 255 275 300
Phosphoric acid   190 240 285 330 340 375 400 460
Nitric acid   115 155 190 250 105 150 185 210
Aldehydes          
HMF -0.37 8 10* 22* 37* 63* 12 26 42 63
Furfural 0.41 2 8* 17* 27* 52* 9 16 26 42
Syringaldehyde 11 0.99 8 11 18 26 40 5 10 14 28
Vanillin 1.21 2 2 4 9 20 1 3 5 13
4-Hydroxybenzaldehyde 1.35 5 2 5 10 25 3 7 12 25
Alcohols          
Furfuryl alcohol 0.28 2 60 100 140 220 60 100 140 205
Ethanol -0.24 2 910* 1350* 1735* 2170* 950 1260 1600 2170
  1. 1 Estimated Values from Yaws’ Handbook of Thermodynamic and Physical Properties of Chemical Compounds © 2003 Knovel, Table: Solubility in Water and Octanol-Water Partition Coefficient.
  2. 2 Measured Values from Yaws’ Handbook of Thermodynamic and Physical Properties of Chemical Compounds © 2003 Knovel, Table: Solubility in Water and Octanol-Water Partition Coefficient.
  3. 3 Handbook of Environmental Data on Organic Chemicals (4th Edition) © 2001 John Wiley & Sons; Table: Physical and Environmental Data on Organic Chemicals (2-Furoic Acid is calculated).
  4. 4 Perry’s Chemical Engineers’ Handbook (7th Edition) © 1997 McGraw-HillChemicals; Table: Safety Properties of Common Solvents.
  5. 5 Chemical Properties Handbook © 1999 McGraw-Hill; Table:
  6. 6 Exploring QSAR,Hydrophobic, Electronic, and Steric Constants Hansch C, Leo A, and Hoekman D 1995 Amer. Chem. Soc., Washington DC.
  7. 7 Octanol-Water Partition Coefficients: Fundamentals and Physical Chemistry. Sangster J 1994 Wiley, New York.
  8. 8 Partition coefficients calculated from Biobyte, Inc. (Clarement, CA), cited [1618].
  9. 9 Inhibitory concentrations (IC) obtained for the NH4+ cation of the acids, except for oxalic acid in which case, K+ was used).
  10. 10 Inhibitory concentrations in bold were extrapolated from the inhibition curve.
  11. 11 Indicated compounds were dissolved in DMSO (< 5% (v/v)) because of low solubilities.
  12. * Reported [22].