Figure 5

Three Multiple Em for Motif Elicitation (MEME) motifs mapped to the predicted structures of AA10. MEME was used to identify motifs from four separate subclades A to D from the phylogenetic tree of AA10. The loops are shown for illustration purposes only. The number of sequences in each clade is as follows: subclade A (68 sequences), clade B (29 sequences), clade C (77 sequences), and clade D (122 sequences). These motifs were mapped to the structures that were predicted using iterative threading assembly refinement algorithm (I-TASSER), as shown in (a). Motif1 is shown in cyan color, motif2 is shown in blue and motif3 is shown in red. (b) MEME motifs mapped to the sequences from the available crystallographic structures of AA10 and AA9, showing the distribution of three motifs in the sequence. Sequence logo of (c) motif1 (cyan), (d) motif2 (blue), and (e) motif3 (red) in the available structures.