TY - JOUR AU - Fernández-Fueyo, Elena AU - Ruiz-Dueñas, Francisco J. AU - Martínez, Angel T. PY - 2014 DA - 2014/07/24 TI - Engineering a fungal peroxidase that degrades lignin at very acidic pH JO - Biotechnology for Biofuels SP - 114 VL - 7 IS - 1 AB - Ligninolytic peroxidases are divided into three families: manganese peroxidases (MnPs), lignin peroxidases (LiPs), and versatile peroxidases (VPs). The latter two are able to degrade intact lignins, as shown using nonphenolic lignin model compounds, with VP oxidizing the widest range of recalcitrant substrates. One of the main limiting issues for the use of these two enzymes in lignocellulose biorefineries (for delignification and production of cellulose-based products or modification of industrial lignins to added-value products) is their progressive inactivation under acidic pH conditions, where they exhibit the highest oxidative activities. SN - 1754-6834 UR - https://doi.org/10.1186/1754-6834-7-114 DO - 10.1186/1754-6834-7-114 ID - Fernández-Fueyo2014 ER -