Figure 2

Tightly co-expressed genomic regions with candidate regulatory genes. The expression array dataset described in [8] was searched for genomic regions with co-expressed genes. The regions containing a selected candidate regulatory gene with adjacent genes belonging to the same Mfuzz gene expression clusters as the major cellulase and hemicellulase genes are shown. The genomic location of the genes is indicated as scaffold number, start and end position, and strand in the scaffold as in T. reesei database 2.0 [45]. Gene annotation is as in T. reesei database 2.0. The expression data of the genes in the induction dataset with cellulose, wheat and spruce material, and sophorose is shown as the expression cluster number (Mfuzz) and fold change of the transcript signals in the induced cultures as compared to the uninduced control cultures at the same time point. The intensity of the red color and blue color indicates the strength of positive and negative fold changes as compared to the uninduced control cultures, respectively. AV, Avicel cellulose; SO, sophorose; SP, spruce; WH, wheat straw.