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Table 1 Selected genes with significant expression level changes in spo0A mutant in the category of amino acid transport and metabolism

From: Improvement of cellulose catabolism in Clostridium cellulolyticum by sporulation abolishment and carbon alleviation

  Cellulose     Cellobiose   
ORF Annotation Log2R Z-score ORF Annotation Log2R Z score
0078 Prephenate dehydratase 4.69 1.60 0303 Acetolactate synthase, large subunit 2.35 4.66
0127 3-Isopropylmalate dehydratase, small subunit 3.69 1.51     
0128 3-isopropylmalate dehydrogenase 3.22 1.98     
3435 Ketol-acid reductoisomerase 3.66 1.77     
3218 Tryptophan synthase, beta subunit 2.50 1.67     
1129 Carboxynorspermidine decarboxylase 2.43 1.77     
0155 Orn/Lys/Arg decarboxylase major region 2.40 1.52     
  1. Genes related to valine, leucine and isoleucine biosynthesis in spo0A mutant were detected to be upregulated, including Ccel_0127 encoding 3-isopropylmalate dehydratase small subunit, Ccel_0128 encoding 3-isopropylmalate dehydrogenase, Ccel_3435 encoding ketol-acid reductoisomerase, and Ccel_0303 encoding acetolactate synthase large subunit. ORF, open reading frame.