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Table 3 Comparison of K. pneumoniae parent strain (KG1), Δ adhE and the Δ pta using several carbon sources in a 36-h flask cultivation, the values represent mean ± SD

From: Effect of the inactivation of lactate dehydrogenase, ethanol dehydrogenase, and phosphotransacetylase on 2,3-butanediol production in Klebsiella pneumoniae strain

Strain Carbon source (50 g/L) Consumed carbon source (g/L) 2,3-Butanediol (g/L) Lactate (g/L) Acetate (g/L) Acetoin (g/L) Ethanol (g/L) Biomass (g/L) 2,3-Butanediol yield (g/g)
KG1 Glucose 49.29 ± 0.65 16.76 ± 0.22 3.62 ± 0.21 4.52 ± 0.45 1.73 ± 0.09 2.67 ± 0.16 4.80 ± 0.32 0.34
Lactose 49.39 ± 0.59 16.28 ± 0.13 2.95 ± 0.15 2.98 ± 0.28 3.26 ± 0.11 4.16 ± 0.32 2.80 ± 0.43 0.33
Fructose 44.84 ± 0.61 14.41 ± 0.16 2.27 ± 0.12 2.85 ± 0.33 2.46 ± 0.13 3.22 ± 0.25 4.06 ± 0.52 0.32
Galactose 34.89 ± 0.48 10.27 ± 0.11 3.33 ± 0.15 2.83 ± 0.32 1.80 ± 0.10 2.64 ± 0.28 3.89 ± 0.18 0.29
Maltose 49.20 ± 0.51 17.30 ± 0.21 2.03 ± 0.14 2.79 ± 0.16 3.56 ± 0.12 4.45 ± 0.45 3.87 ± 0.21 0.35
ΔadhE Glucose 49.27 ± 0.42 23.65 ± 0.25 1.35 ± 0.09 2.05 ± 0.12 0.60 ± 0.04 0.52 ± 0.04 3.95 ± 0.52 0.48
Lactose 17.76 ± 0.25 8.76 ± 0.12 1.61 ± 0.11 3.85 ± 0.42 2.01 ± 0.08 0.36 ± 0.06 1.76 ± 0.35 0.49
Fructose 49.47 ± 0.52 21.40 ± 0.24 1.48 ± 0.13 1.58 ± 0.12 0.83 ± 0.06 0.94 ± 0.02 3.25 ± 0.28 0.43
Galactose 36.35 ± 0.42 14.05 ± 0.42 0.73 ± 0.07 1.96 ± 0.09 3.70 ± 0.21 0.65 ± 0.03 2.99 ± 0.42 0.39
Maltose 49.49 ± 0.47 18.18 ± 0.23 2.96 ± 0.10 1.27 ± 0.08 4.58 ± 0.24 0.91 ± 0.08 4.27 ± 0.25 0.36
Δpta Glucose 49.27 ± 0.54 20.20 ± 0.62 0.77 ± 0.09 3.15 ± 0.11 2.31 ± 0.15 1.69 ± 0.32 3.40 ± 0.52 0.41
Lactose 10.10 ± 0.25 2.98 ± 0.11 0.96 ± 0.07 2.01 ± 0.10 _ 0.30 ± 0.02 1.01 ± 0.46 0.30
Fructose 49.51 ± 0.55 18.36 ± 0.32 1.01 ± 0.10 2.20 ± 0.09 2.81 ± 0.11 1.87 ± 0.14 2.96 ± 0.26 0.37
Galactose 39.49 ± 0.23 11.88 ± 0.12 0.19 ± 0.06 1.98 ± 0.12 1.56 ± 0.14 1.29 ± 0.21 3.27 ± 0.43 0.30
  Maltose 40.28 ± 0.54 14.57 ± 0.24 4.68 ± 0.08 2.50 ± 0.14 1.91 ± 0.12 3.26 ± 0.33 3.74 ± 0.44 0.36