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Table 2 Identified reactions that contribute significantly to the predicted maximum NADH production rate

From: Theoretical exploration of optimal metabolic flux distributions for extracellular electron transfer by Shewanella oneidensisMR-1

Reaction ID

Flux

Enzyme

EC Number

Reaction

Subsystems

Min

Max

GAPD

-8.745

-0.0559

Glyceraldehyde-3-phosphate dehydrogenase (NAD)

1.2.1.12

[c] : g3p + nad + pi<==>13dpg + h + nadh

Glycolysis/Gluconeogenesis

ICDHxi

0

54.09

Isocitrate dehydrogenase (NAD)

1.1.1.41

[c] : icit + nad -->akg + co2 + nadh

Citrate cycle (TCA)

THD5

0

54.09

NAD transhydrogenase

N/A

[c] : nad + nadph -->nadh + nadp

Energy metabolism

  1. (Note: The flux values are calculated by multiplying the reaction flux (not shown) and the stoichiometry coefficient of the NADH.)
  2. The flux ranges were calculated from the FATMIN algorithm. N/A, not available.