Figure 1
From: Metabolic engineering of Methylobacterium extorquens AM1 for 1-butanol production
Ethylmalonyl-CoA pathway in M. extorquens showing intermediates for 1-butanol production. PhaA, β-ketothiolase; PhaB, acetoacetyl-CoA reductase; CroR, crotonase; Ccr, crotonyl-CoA carboxylase/reductase; Ter, trans-2-enoyl-CoA reductase; AdhE2, bifunctional aldehyde/alcohol dehydrogenase. Gray lines represent methylotrophic pathways used exclusively in C1 assimilation. Dashed lines represent the heterologous pathway for 1-butanol production.