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Table 1 IC 50 (g/L)* for furfural and 5-hydroxymethylfurfural in thermophilic bacteria and ethanologenic microorganisms

From: A comparative multidimensional LC-MS proteomic analysis reveals mechanisms for furan aldehyde detoxification in Thermoanaerobacter pseudethanolicus 39E

Organism

Furfural

5-HMF

YE (% w/v)

Carbon (% w/v)

Time (h)

Temp (°C)

pH

Ref.

T. pseudethanolicus 39E

3

2 - 3

0.1

0.7

12

65

7.0

TS

T. pseudethanolicus 39E

3 - 4

2 - 3

0.1

0.7

24

65

7.0

TS

Bacillus coagulans MXL-9

2.5 - 5

5

0.5#

5-10

24

50

7.0

[29]

C. saccharolyticus

1 - 2

1 - 2

0.1

1

16, 40

72

7.0

[30]

Thermoanaerobacterium strain AK17†

2

3

0.2

0.4

120

60

6.0

[11]

Tm. thermosaccharolyticum

1.25

1

0.2

1

40

60

7.0

[31]

Thermotoga neapolitana

2 - 4

2 - 4

0.1

1

16, 40

80

7.0

[30]

E. coli LY180

1 - 1.5

nd

none

5

48

37

6.5

[23]

E. coli LY180

< 0.4

nd

none

5 (xyl)

48

37

6.5

[23]

E. coli LY180

1.5

nd

0.1

5 (xyl)

48

37

6.5

[23]

S. cerevisiae CBS 1200

0.5

< 1

0.3

2

24

26

5.8

[32]

S. cerevisiae NSI 113

2

nd

0.3

1

48

30

5.3

[33]

Z. mobilis ATCC 10988

2

5

0.3

2

24

30

5.6

[32]

  1. *Concentration at which 50% inhibition of growth occurred with furfural and 5-hydroxymethylfurfural (5-HMF). Values determined in this study are highlighted in boldface. #Medium also included 1% tryptone; †measured as 50% inhibition of ethanol production; YE, yeast extract; nd, not determined; xyl, xylose; TS, This study.