Fig. 7
Enhancing myo-inositol synthesis improves strain tolerance to FAP. a The schematic of overexpressing INO1 to up-regulate myo-inositol synthesis. b The effect of INO1 overexpression on the relative abundance of myo-inositol under FAP stress. c The effect of INO1 overexpression on the growth behaviors under FAP stress. d The effect of INO1 overexpression on the glucose consumption and ethanol production under FAP stress. The strain BY4742/pRS426 and BY4742/INO1 were cultivated in SC-Ura medium in the presence of 0.8Â g/L furfural, 3.0Â g/L acetic acid and 0.3Â g/L phenol. Results are the mean of duplicate experiments and error bars indicate SD