High production of 2,3-butanediol from biodiesel-derived crude glycerol by metabolically engineered Klebsiella oxytoca M1

Table 4 Comparison of 2,3-BDO production from glycerol

Host bacteria	Carbon sources	Culture mode	Concentration (g/L)		2,3-BDO productivity (g/LH)	2,3-BDO yield (g/g)	References
Host bacteria	Carbon sources	Culture mode	2,3-BDO	1,3-PDO	2,3-BDO productivity (g/LH)	2,3-BDO yield (g/g)	References
K. pneumoniae	Pure glycerol	Fed batch	49.2	10.6	0.18	0.36	[20]
K. pneumoniae	Pure glycerol	Fed batch	70	16.3	0.47	0.39	[21]
B. amyloliquefaciens	Crude glycerol	Fed batch	43.1	–	0.45	0.38	[25]
B. amyloliquefaciens	Crude glycerol + molasses	Fed batch	83.3	–	0.87	0.42	[25]
K. oxytoca	Crude glycerol	Batch flask	4.8	8.4		0.14	[19]
K. oxytoca	Crude glycerol + glucose	Batch flask	8.0	3.8		0.22	[19]
K. oxytoca M3	Pure glycerol	Fed batch	115.0	6.9	1.01	0.39	This study
K. oxytoca M3	Crude glycerol	Fed batch	131.5	0	0.84	0.44	This study

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