Skip to main content

Table 4 Summary of the most relevant succinic acid production studies using A. succinogenes and a potentially scalable, renewable feedstock with pure sugar studies given for comparison

From: Continuous succinic acid production by Actinobacillus succinogenes on xylose-enriched hydrolysate

Substrate (feedstock)

Pretreatment method

Mode

q SA (g L−1 h−1)a

C SA (g L−1)b

Y sSA (g g−1)c

References

Corn stover (xylose, glucose, arabinose, galactose)

Pilot scale: deacetylation followed by dilute sulphuric acid hydrolysis

Continuous

1.77

39.6

0.78

This study

Xylose

–

Continuous

2.64

32.5

0.77

This study

Xylose

–

Continuous

3.41

29.4

0.68

[46]

Xylose (60 g L−1)

–

Batch

0.94

38.4

0.70

[37]

Corn stover

Pilot scale: deacetylation followed by dilute sulphuric acid hydrolysis (DDAP-H)

0.30

42.8

0.74

Pilot scale: dilute sulphuric acid hydrolysis (DAP-H)

0.12

17.0

0.52

Mock DDAP-H (xylose, glucose, arabinose, galactose, inhibitors, low acetate)

–

0.61

43.8

0.68

Mock DAP-H (xylose, glucose, arabinose, galactose, inhibitors, high acetate)

–

0.61

43.7

0.72

Sugarcane bagasse (xylose)

Dilute sulphuric acid hydrolysis

Batch

1.01

22.5

0.43

[57]

Wheat (glucose)

Enzymatic hydrolysis

Batch

1.01

35.6

0.82

[58]

1.57

64.2

0.81

[59]

0.91

62.1

1.02

[60]

Corn fibre (glucose, xylose, arabinose)

Dilute sulphuric acid hydrolysis by autoclaving

Batch

0.98

35.4

0.73

[61]

0.63

47.0

0.68

[62]

Corn stover (glucose, xylose, arabinose)

Dilute sulphuric acid hydrolysis followed by cellulose treatment

Batch

1.08

56.4

0.73

[30]

Sugarcane molasses (sucrose, glucose, fructose)

Sulphuric acid treatment of crude molasses

Batch

1.30

60.7

0.81

[63]

Fed-batch

1.40

64.7

0.86

Batch

0.97

57.9

0.69

[64]

Fed-batch

1.07

64.3

0.76

Glucosed

–

Continuous

10.8

32.5

0.90

[12]

–

Fed-batch

2.77

98.7

0.89

[65]

  1. The highest SA productivity, concentration and yield for each study are shown
  2. aSuccinic acid productivity
  3. bSuccinic acid concentration
  4. cYield of succinic acid on carbohydrate substrate(s)
  5. dComparative baseline study