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Fig. 1 | Biotechnology for Biofuels

Fig. 1

From: Engineering Escherichia coli for high-yield geraniol production with biotransformation of geranyl acetate to geraniol under fed-batch culture

Fig. 1

Production of geraniol via the MVA pathways used in this study. Enzymes involved in this pathway: MvaE, E. faecalis acetyl-CoA acetyltransferase/HMG-CoA reductase; MvaS, E. faecalis HMG-CoA synthase; ERG12, S. cerevisiae mevalonate kinase; ERG8, S. cerevisiae phosphomevalonate kinase; ERG19, S. cerevisiae mevalonate pyrophosphate decarboxylase; IDI1, S. cerevisiae IPP isomerase; GPPS2, A. grandis geranyl diphosphate synthase; GES, O. basilicum synthase was optimized to the preferred codon usage of E. coli. Pathway intermediates: A-CoA, acetyl-CoA; AA-CoA, acetoacetyl-CoA; HMG-CoA, hydroxymethylglutaryl-CoA; Mev-P, mevalonate 5-phosphate; Mev-PP, mevalonate pyrophosphate. IPP isopentenyl pyrophosphate, DMAPP dimethylallyl pyrophosphate, GPP geranyl diphosphate

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