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Table 1 Optimized parameters of the enzymatic hydrolysis and yeast fermentation

From: Model-based optimization and scale-up of multi-feed simultaneous saccharification and co-fermentation of steam pre-treated lignocellulose enables high gravity ethanol production

Parameters

Optimized value

95 % Confidence intervals

Unit

Description

\(k_{\text{ad}}\)

0.27

[0.03, 0.5]

g solid FPU−1 h−1

Adsorption rate constant

\(k\)

0.016

[0.009, 0.03]

g cellulose FPU−1 h−1

Hydrolysis rate constant

\(K_{\text{G}}\)

6.13

[2.7, 13.8]

g L−1

Inhibition constant of glucose in cellulose hydrolysis

\(\gamma\)

0.028

[0.01, 0.08]

Proportionality factor between xylan and cellulose degradation

\(K_{\text{iEtOH}}\)

16.6

Assumeda

g L−1

Inhibition constant of ethanol in cellulose hydrolysis

\(q_{\text{G}}\)

1.6

Assumeda

g g−1 h−1

Specific glucose uptake rate by yeast

\(K\)

0.01

Assumedb

g L−1

Saturation constant of glucose uptake

\(Y_{\text{EtOH}}\)

0.42

Assumedb

g g−1

Ethanol yield on glucose

\(\alpha\)

0.026

Assumedb

h−1

Pre-exponential factor of the ethanol-induced death rate coefficient

\(\beta\)

0.0037

Assumedb

L g−1

Exponential factor of the ethanol-induced death rate coefficient

  1. aModified from [9]
  2. bModified from [29]