Fig. 1
From: Metabolic engineering of Bacillus subtilis for chiral pure meso-2,3-butanediol production
The meso-2,3-BD biosynthetic pathway in B. subtilis. Enzymes overexpressed or introduced are underlined and depicted in green, and those interrupted are shown in red with a cross. Expanded names of enzymes and their coding genes: ALS acetolactate synthase, alsS; ALD acetolactate decarboxylase, alsD; ACK acetate kinase, ack; ALDH acetaldehyde dehydrogenase, adh; ADH alcohol dehydrogenase, ack; LDH lactate dehydrogenase, ldh; PDH pyruvate dehydrogenase, pdhABCD; PTA phosphotransacetylase, pta; PYC pyruvate carboxylase; E1, d-(−)-butanediol dehydrogenase (EC 1.1.1.4), bdhA; E2, L-(+)-butanediol dehydrogenase (EC 1.1.1.76), budC