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Table 1 KEGG biological pathways of differentially expressed genes

From: DNA microarray of global transcription factor mutant reveals membrane-related proteins involved in n-butanol tolerance in Escherichia coli

KEGG pathway Gene Expression difference Description
ABC transporters modA 2.28↓ Molybdate-binding periplasmic protein precursor
alsB 2.83↑ Putative LACI-type transcriptional regulator
artM 2.18↓ Arginine 3rd transport system permease protein
fepC 2.05↑ ATP-binding component of ferric enterobactin transport
fepD 5.63↑ Ferric enterobactin transport system permease protein
pstS 2.57↑ Periplasmic phosphate-binding protein
Ascorbate and aldarate metabolism sgaE 2.08↑ Putative epimerase
ulaF 2.56↑ Putative epimerase
ulaA 2.65↑ Hypothetical protein
ECs5173 2.64↑ Putative hexulose-6-phosphate isomerase
Glyoxylate and dicarboxylate metabolism aceA 2.97↑ Isocitrate lyase
ybbQ 7.51↑ 2-Hydroxy-3-oxopropionate reductase
glxR 9.86↑ Putative oxidoreductase
aceB 3.02↑ Malate synthase A
acnA 3.04↓ Aconitate hydrase 1
hyi 9.53↑ Glyoxylate-induced protein
gcl 10.60↑ Glyoxylate carboligase
glcB 7.86↑ Malate synthase G
glcD 12.78↑ Glycolate oxidase subunit D
glcF 22.60↑ Glycolate oxidase iron–sulfur subunit
Oxidative phosphorylation atpC 2.00↑ Membrane-bound ATP synthase
cydA 2.07↑ Cytochrome d terminal oxidase
cydB 2.18↑ Cytochrome d terminal oxidase polypeptide subunit II
Pentose phosphate pathway tktA 2.31↑ Transketolase 1
gntK 2.53↑ Gluconokinase 2
talA 2.36↓ Transaldolase A
prs 2.61↑ Phosphoribosylpyrophosphate synthetase
ECs3810 2.19↑ Transketolase 1 isozyme
Phenylalanine metabolism mhpD 2.24↑ 2-Keto-4-pentenoate hydratase
mhpC 2.41↑ 2-Hydroxy-6-ketonona-2,4-dienedioic acid hydrolase
Propanoate metabolism tdcD 6.46↑ Putative kinase
tdcE 6.81↑ Probable formate acetyltransferase 3
prpD 3.39↓ Orf, hypothetical protein
prpB 3.72↓ Putative phosphonomutase 2
accC 2.48↑ Acetyl CoA carboxylase
accB 2.23↑ BCCP subunit; carrier of biotin
ECs3995 6.59↑ Putative kinase
Pyruvate metabolism poxB 3.06↓ Pyruvate oxidase
glcB 7.86↑ Malate synthase G
accC 2.48↑ Acetyl CoA carboxylase
accB 2.23↑ BCCP subunit; carrier of biotin
gloB 2.08↓ Probable hydroxyacylglutathione hydrolase
aceB 3.02↑ Malate synthase A
pps 2.12↑ Phosphoenolpyruvate synthase
tdcE 6.81↑ Probable formate acetyltransferase 3
ECs0957 3.03↓ Pyruvate oxidase
Ribosome rpsQ 2.22↑ 30S ribosomal subunit protein S17
rplQ 2.01↑ 50S ribosomal subunit protein L17
rpmA 2.01↑ 50S ribosomal subunit protein L27
rplU 2.28↑ 50S ribosomal subunit protein L21
rpmD 2.04↑ 50S ribosomal subunit protein L30
Starch and sucrose metabolism ybhC 2.06↑ Putative pectinesterase
treF 2.36↓ Cytoplasmic trehalase
malP 2.19↓ Maltodextrin phosphorylase
otsA 2.32↓ Trehalose-6-phosphate synthase
Two-component system rcsF 2.40↑ Protein rcsF
ompC 2.07↑ Outer membrane protein 1b
pstS 2.57↑ High-affinity phosphate-specific transport system
Ubiquinone and other terpenoid-quinone biosynthesis entC 3.10↑ Isochorismate hydroxymutase 2
menE 7.17↓ o-Succinylbenzoate-CoA ligase
ubiX 2.24↑ 3-Octaprenyl-4-hydroxybenzoate carboxy-lyase
menC 9.10↓ o-Succinylbenzoyl-CoA synthase
Phenylalanine. tyrosine and tryptophan biosynthesis trpE 3.15↑ Anthranilate synthase component I
trpD 5.04↑ Anthranilate synthase component II
aroH 2.02↑ 3-Deoxy-D-arabinoheptulosonate-7-phosphate synthase
ECs1836 2.97↑ Anthranilate synthase component I
ECs1833 2.46↑ Tryptophan synthase beta protein
  1. “↑” Represents up-regulated, “↓” represents down-regulated