Fig. 6

Relative protein abundance. Abundance was determined based on matched-ion intensity (MIT) and is reported in arbitrary units. Proteins that were not detected were plotted with a low-level log-normal distribution value. Each point represents the average of two biological replicates. For panel a, all the gene deletions proteins are in red color, and some significantly upregulated genes are noted in green color. For panel b, proteins were included for selection that are thought to play a role in central metabolism, electron transfer, and ethanol production. Red ovals indicate the abundances decreased significantly between AG601 and LL1210; Green ovals indicate the abundances increase significantly; Gray ovals indicated no significant difference in the abundances. The solid diagonal line represents a 1:1 correspondence in protein abundance between target and control strains. The dashed lines indicate twofold changes in abundance