Table 5 Citric acid and by-product synthesis by various Y. lipolytica strains in CA Fermentation Medium (pH 3.0)
From: A novel strain of Yarrowia lipolytica as a platform for value-added product synthesis from glycerol
Strain | Time (h) | Biomass (g/L) | Glycerol (g/L) | Erythritol (g/L) | Arabitol (g/L) | Mannitol (g/L) | Citric acid (g/L) | α-Ketoglutaric acid (g/L) |
|---|---|---|---|---|---|---|---|---|
A101 | 24 | 12.1 ± 4.4 | 127.6 ± 12.1 | 3.9 ± 1.8 | 0.5 ± 0.2 | 1.5 ± 0.6 | 0 | 1.8 ± 0.8 |
48 | 22.8 ± 3.2 | 68.1 ± 12.1 | 14.0 ± 3.0 | 1.7 ± 0.6 | 12.2 ± 1.3 | 0.9 ± 1.2 | 2.0 ± 0.1 | |
72 | 26.0 ± 4.8 | 16.3 ± 3.1 | 15.4 ± 3.9 | 2.7 ± 1.1 | 27.7 ± 7.6 | 4.4 ± 0.3 | 0.8 ± 0.1 | |
96 | 26.2 ± 2.8 | 0 | 6.2 ± 2.8 | 2.7 ± 0.1 | 26.1 ± 5.9 | 4.4 ± 1.8 | 0.8 ± 0.1 | |
AJD pADUTGut1 | 24 | 19.1 ± 1.1 | 101.4 ± 0.8 | 11.1 ± 2.0 | 2.6 ± 1.3 | 2.4 ± 1.1 | 2.0 ± 1.5 | 0.4 ± 0.1 |
48 | 24.0 ± 2.5 | 0 | 41.4 ± 0.1 | 6.8 ± 2.3 | 18.4 ± 2.3 | 33.0 ± 3.4 | 0.6 ± 0.8 | |
72 | 24.0 ± .0.2 | 0 | 10.3 ± 2.4 | 5.8 ± 0.8 | 18.4 ± 1.6 | 47.2 ± 1.4 | 0 | |
96 | 21.7 ± 1.8 | 0 | 0.7 ± 0.2 | 6.2 ± 1.0 | 18.3 ± 3.3 | 60.4 ± 6.8 | 0 | |
AJD pADUTGut2 | 24 | 15.2 ± 2.1 | 98.4 ± 4.9 | 9.8 ± 0.7 | 1.2 ± 0.9 | 1.5 ± 0.1 | 1.2 ± 0.6 | 1.3 ± 0.1 |
48 | 25.4 ± 3.9 | 14.0 ± 3.1 | 34.5 ± 3.9 | 3.1 ± 2.9 | 14.6 ± 2.4 | 29.8 ± 2.8 | 0 | |
72 | 24.6 ± 2.1 | 0 | 2.5 ± 1.5 | 3.1 ± 2.9 | 17.9 ± 5.6 | 53.6 ± 8.0 | 0 | |
96 | 24.1 ± 1.0 | 0 | 0 | 2.0 ± 1.4 | 13.7 ± 2.5 | 54.3 ± 4.6 | 0 | |
AJD pADUTGut1/2 | 24 | 16.5 ± 0.5 | 90.6 ± 5.9 | 9.8 ± 0.2 | 1.1 ± 0.5 | 1.7 ± 0.2 | 1.1 ± 0.4 | 1.3 ± 0.1 |
48 | 27.6 ± 1.0 | 19.4 ± 6.4 | 33.4 ± 5.9 | 3.3 ± 1.8 | 15.1 ± 1.3 | 29.8 ± 3.2 | 0.9 ± 0.6 | |
72 | 25.1 ± 0.4 | 0 | 4.2 ± 2.9 | 3.4 ± 1.3 | 20.2 ± 2.0 | 60.1 ± 1.3 | 0 | |
96 | 23.4 ± 1.0 | 0 | 0 | 3.0 ± 0.5 | 16.1 ± 0.7 | 63.9 ± 1.3 | 0 |