TY - JOUR AU - Menendez-Bravo, Simón AU - Roulet, Julia AU - Sabatini, Martín AU - Comba, Santiago AU - Dunn, Robert AU - Gramajo, Hugo AU - Arabolaza, Ana PY - 2016 DA - 2016/10/14 TI - High cell density production of multimethyl-branched long-chain esters in Escherichia coli and determination of their physicochemical properties JO - Biotechnology for Biofuels SP - 215 VL - 9 IS - 1 AB - Microbial synthesis of oleochemicals derived from native fatty acid (FA) metabolism has presented significant advances in recent years. Even so, native FA biosynthetic pathways often provide a narrow variety of usually linear hydrocarbons, thus yielding end products with limited structural diversity. To overcome this limitation, we took advantage of a polyketide synthase-based system from Mycobacterium tuberculosis and developed an Escherichia coli platform with the capacity to synthesize multimethyl-branched long-chain esters (MBE) with novel chemical structures. SN - 1754-6834 UR - https://doi.org/10.1186/s13068-016-0631-x DO - 10.1186/s13068-016-0631-x ID - Menendez-Bravo2016 ER -