Production of l(+)-lactic acid from acid pretreated sugarcane bagasse using Bacillus coagulans DSM2314 in a simultaneous saccharification and fermentation strategy

Table 5 Production of lactic acid from pretreated lignocellulosic material using either a separate enzymatic hydrolysis and fermentation process (SHF), or a combined process (SSF)

	Microorganism	Feedstock	Chemical pretreatment	SSF/SHF	Detoxification	Enzymatic hydrolysis	EH^a (h)	Inoculum (% v/v)	C_LA (g/l)	Y _Lc/LA (%)	Y _S/LA (%)	Q _{LA F} (g/l/h)	Q _{LA, O} (g/l/h)	Source
1	P. acidilactici DQ2	Corn stover	2.5% H2SO4, 3 m, 190C	SSF	Biological 5 days	Acc 1000 15 FPU/g DW	8	20	101.6	77.2	ND	1.06	0.45	Zhao et al. [25]
2	Bacillus sp. NL01	Corn stover	3% H2SO4 2 h RT, 5 m 170C, SE	SHF	Centrifugation after EH	Cell 1.5L 15 FPU/g DW + Novo 188 30 CBU/g DW	48	8	61.3	ND	70	1.46	0.67	Ouyang et al. [21]
3	B. coagulans DSM2314	Wheat straw	10% NaOH, 16 h, 85C	SSF	None	GC220 18 FPU/g DW	2	20	40.7	43	81	0.74	0.56	Maas et al. [11]
4	E. faecalis RKY1	Oak wood	0.5%H2SO4 24 h RT, 5 m 215C, SE	SHF	Centrifugation after EH	Cell 1.5L 15 FPU/g DW + Novo 188 30 CBU/g DW	48	?	93	ND	80	1.7	0.74	Wee et al. [26]
5	B. coagulans DSM2314	Sugarcane bagasse + LF	0.72% H2SO4, 15 m, 170C, SE	SSF	None	GC220 13.4 FPU/g DW	5	5	64.1	74	80	0.78	0.72	This article
6	B. coagulans DSM2314	Sugarcane bagasse + LF	0.72% H2SO4, 15 m, 170C, SE	SSF	None	GC220 13.4 FPU/g DW	5	5 (Fu P)	74.6	87	94	0.92	0.79	This article
7	B. coagulans DSM2314	Sugarcane bagasse	0.72% H2SO4, 15 m, 170C, SE	SSF	None	GC220 15.2 FPU/g DW	4	5 (Fu P)	70.4	83	90	1.14	0.98	This article
8	B. coagulans DSM2314	Sugarcane bagasse	0.72% H2SO4, 15 m, 170C, SE	SSF (two-stage)	None	GC220 15.2 FPU/g DW	6	5(Fu P)	58.7	73	90	1.81	1.33	This article

LF liquid fraction, RT room temperature, EH enzymatic hydrolysis. Acc accelerase, Cell cellulast, Novo novozymes. nd not determined, Fu P furfural preculture, C _LA concentration of lactic acid at the end of the SSF in g/l, Y _Lc/LA lactic acid production yield on total lignocellulosic sugars in W/W, Y _s/LA estimated conversion efficiency of sugar monomers to lactic acid in W/W, Q _LA.F average volumetric lactic acid productivity during fermentation phase in g/l/h, Q _LA.O average volumetric lactic acid productivity over the total process in g/l/h, Fu P inoculum precultivated in the presence of 1 g/l furfural
^aEnzymatic hydrolysis time required during SHF, or pre-hydrolysis time prior to inoculation during SSF

ISSN: 2731-3654