Fig. 1From: Self-regulated 1-butanol production in Escherichia coli based on the endogenous fermentative controlSynthetic 1-butanol pathway expressed in the mixed-acid fermentation mutant. The mixed-acid mutant strain (ΔldhA ΔfrdBC ΔadhE Δpta) relies on the CoA-dependent 1-butanol pathway to recycle the NADH generated in glycolysis and to restore anaerobic growth. Different microbial sources of the 1-butanol pathway enzymes are shown in the parenthesis: EC, Escherichia coli; CA, Clostridium acetobutylicum; TD, Treponema denticola; CB, Candida boidinii Back to article page