Fig. 2

Heat map of C. thermocellum transcriptomic response to exogenous acetate. Hierarchical clustering of the 439 genes significantly (FDR < 0.05) differentially expressed (log₂ ± 1) in at least one of the listed comparisons. Genes were grouped into ten clusters using the JMP Genomics 6 software. Comparisons shown A Wild type with acetate versus without acetate; B ΔhydG versus wild type, both without acetate; C ΔhydG with acetate versus without acetate; D ΔhydG Δech with acetate versus without acetate; E ΔhydG Δech versus ΔhydG, both without acetate; and F ΔhydG Δech versus ΔhydG, both with acetate. Blue and yellow indicate decreased expression and increased expression, respectively, in each comparison. Data are the average of three independent biological replicates. Cluster numbers cross-reference to Additional file 3: Data set S1