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Fig. 3 | Biotechnology for Biofuels

Fig. 3

From: Integrated omics analyses reveal the details of metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrass

Fig. 3

Glycolytic pathway. All the enzymes shown in the pathways were detected in mass spectrometry experiments. The red arrow in the pathway refers to the significant enzymes that belong to clusters 3 or 4. The green arrow refers to the significant enzymes that belong to clusters 1 and 2. The blue arrow refers to the enzymes that were detected in mass spectrometry but were not significantly changing over time. 1. Cellulosomes; 2. Cellodextrin ABC transporters Cthe_1019, 1020, 1862; 3. Cellodextrin phosphorylase Cthe_2989; 4. Phosphoglucomutase Cthe_1265; 5. Glucokinase Cthe_0390; 6. Gluco-6-P-Isomerase Cthe_0217; 7. Phosphofructokinase Cthe_0347; 8. Fructose-bis-P-aldolase Cthe_0349, 0319; 9. Glyceraldehyde-3-P-dehydrogenase Cthe_0137; 10. Triose-phosphate isomerase Cthe_0139; 11. Phosphoglycerate kinase Cthe_0138; 12. Phosphoglycerate mutase Cthe_0140; 13. Enolase Cthe_0143; 14. PEP Carboxykinase Cthe_2874; 15. Malate dehydrogenase Cthe_0345; 16. Malic enzymes Cthe_0344; 17. Pyruvate phosphate dikinase Cthe_1308; 18. PEP synthase Cthe_1253; 19. Lactate dehydrogenase Cthe_1053; 20. Pyruvate formate lyase Cthe_0506, 0505; 21. Pyruvate ferredoxin oxidoreductase Cthe_2391, 2393; 22. Phosphotransacetylase Cthe_1029; 23. Acetate kinase Cthe_1028; 24. Acetyl CoA synthetase Cthe_0551; 25. Aldehyde dehydrogenase Cthe_0423* and 26. Alcohol dehydrogenase Cthe_0423*, 0394, 2579 (*bifunctional enzymatic activity)

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