Fig. 3From: Integrated omics analyses reveal the details of metabolic adaptation of Clostridium thermocellum to lignocellulose-derived growth inhibitors released during the deconstruction of switchgrassGlycolytic pathway. All the enzymes shown in the pathways were detected in mass spectrometry experiments. The red arrow in the pathway refers to the significant enzymes that belong to clusters 3 or 4. The green arrow refers to the significant enzymes that belong to clusters 1 and 2. The blue arrow refers to the enzymes that were detected in mass spectrometry but were not significantly changing over time. 1. Cellulosomes; 2. Cellodextrin ABC transporters Cthe_1019, 1020, 1862; 3. Cellodextrin phosphorylase Cthe_2989; 4. Phosphoglucomutase Cthe_1265; 5. Glucokinase Cthe_0390; 6. Gluco-6-P-Isomerase Cthe_0217; 7. Phosphofructokinase Cthe_0347; 8. Fructose-bis-P-aldolase Cthe_0349, 0319; 9. Glyceraldehyde-3-P-dehydrogenase Cthe_0137; 10. Triose-phosphate isomerase Cthe_0139; 11. Phosphoglycerate kinase Cthe_0138; 12. Phosphoglycerate mutase Cthe_0140; 13. Enolase Cthe_0143; 14. PEP Carboxykinase Cthe_2874; 15. Malate dehydrogenase Cthe_0345; 16. Malic enzymes Cthe_0344; 17. Pyruvate phosphate dikinase Cthe_1308; 18. PEP synthase Cthe_1253; 19. Lactate dehydrogenase Cthe_1053; 20. Pyruvate formate lyase Cthe_0506, 0505; 21. Pyruvate ferredoxin oxidoreductase Cthe_2391, 2393; 22. Phosphotransacetylase Cthe_1029; 23. Acetate kinase Cthe_1028; 24. Acetyl CoA synthetase Cthe_0551; 25. Aldehyde dehydrogenase Cthe_0423* and 26. Alcohol dehydrogenase Cthe_0423*, 0394, 2579 (*bifunctional enzymatic activity)Back to article page