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Table 3 The maximum growth rate (μ max) and nerolidol productivities of the engineered strain in flask cultivation on 20 g L−1 glucose

From: Coupling gene regulatory patterns to bioprocess conditions to optimize synthetic metabolic modules for improved sesquiterpene production in yeast

Strain

N6D

NC1D

N391DA

μ max (h−1)

0.16 ± 0.03

0.25 ± 0.01

0.27 ± 0.01

r nerolidol (0–24 h; mg g−1 biomass h−1)

5.73 ± 2.19

5.14 ± 1.29

1.40 ± 0.05

r nerolidol (24–72 h; mg g−1 biomass h−1)

0.18 ± 0.08

0.77 ± 0.09

2.10 ± 0.02

Nerolidol titre (72 h; mg L−1)

124 ± 29

245 ± 8

393 ± 3

Nerolidol C-mole yield (%)

1.7 ± 0.4

3.3 ± 0.1

5.0 ± 0.3

  1. Mean values ± standard deviations are shown (N ≥ 2)