Fig. 3

Analysis of PfCBH1 and TrCBH1 models. a The superposition of the structures of TrCBH1 and PfCBH1. b, c The space-filled structures comparing the substrate tunnel enclosures of CBH1 from P. funiculosum (green colored), and T. reesei (blue colored), respectively. The red-colored regions correspond to the loops along the substrate-binding path, while the catalytic triad region is highlighted in purple. The obviously different regions are highlighted in dotted circles and labeled accordingly. In all frames, the cellononaose ligand from the TrCBH1 Michaelis complex is shown as gray sticks