Trichoderma reesei complete genome sequence, repeat-induced point mutation, and partitioning of CAZyme gene clusters

Table 2 Size distribution of AT-rich blocks in different well-sequenced fungal genomes

Classification	Species	Genome (Mb)	Chromosome number	GC (%)	Numbers of AT-rich blocks of differing lengths (L in kb)^a									Number of long (≥3 kb) AT-rich blocks
Classification	Species	Genome (Mb)	Chromosome number	GC (%)	0.5 ≤ L < 1	1 ≤ L < 3	3 ≤ L < 5	5 ≤ L < 10	10 ≤ L < 15	15 ≤ L < 20	20 ≤ L < 50	50 ≤ L < 100	100≤ L	Number of long (≥3 kb) AT-rich blocks
Pezizomycotina	Trichoderma reesei	34.9	7	51.1 ± 11.6	1845	337	69	38	26	13	9	6	6	167
	Neurospora crassa	41.1	7	48.3 ± 10.0	1064	217	65	67	67	42	86	17	1	345
	Fusarium fujikuroi	43.8	12	47.5 ± 7.3	2110	296	19	44	26	13	14	12	0	128
	Mycosphaerella graminicola	39.7	21	52.1 ± 5.5	1003	1039	277	252	28	9	4	0	0	570
	Penicillium chrysogenum	32.5	4	49.0 ± 5.3	3717	800	30	34	8	6	6	0	0	84
	Aspergillus nidulans	29.8	8	50.4 ± 4.5	2801	528	35	21	3	0	0	0	0	59
Basidiomycota	Ustilago maydis	19.7	23	54.0 ± 3.8	1776	248	1	0	0	0	0	0	0	1
	Cryptococcus neoformans	19.1	14	51.7 ± 4.3	1738	224	0	0	0	0	0	0	0	0
	Coprinopsis cinerea	36.2	13	48.5 ± 3.6	2067	234	6	1	0	0	0	0	0	7
Hemiascomycota	Saccharomyces cerevisiae ^b	12.2	16	38.3 ± 4.1	1021	166	0	0	0	0	0	0	0	0
	Schizosaccharomyces pombe	12.6	3	36.1 ± 4.8	1665	418	5	1	0	0	0	0	0	6
	Candida glabrata	12.3	13	38.6 ± 5.8	1570	386	6	10	2	0	0	0	0	18

^aThe interspersed AT-rich blocks were identified by having AT contents ≥6% higher than that of average DNA in each fungal genome
^bIn Saccharomyces cerevisiae, AT-rich blocks (almost all ≤3 kb) are known to be well correlated with the intergenic regions that bind to the sister chromatin cohesion complexes. There are no or only a few longer AT-rich blocks (≥3 kb) in the genomes of Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida glabrata, Ustilago maydis, Cryptococcus neoformans, and Coprinopsis cinerea