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Table 1 Comparison of fermentation parameters of different strains in shake flask cultivation

From: A new genome-scale metabolic model of Corynebacterium glutamicum and its application

Strain μ max (1/h) DCW (g/L) l-Alanine (g/L) l-Valine (g/L) Citrate (g/L) α-Oxoglutarate (g/L) Succinate (g/L) l-Proline (g/L) Yieldpro (mol/mol)
WT 0.27 ± 0.01 18.62 ± 0.02 4.98 ± 0.07 1.49 ± 0.24 6.88 ± 0.37 1.05 ± 0.14 8.01 ± 0.62
Pro-1 (WTproB*) 0.26 ± 0.00 17.60 ± 0.51 4.85 ± 0.07 1.37 ± 0.27 7.02 ± 0.56 1.08 ± 0.09 7.18 ± 0.80 0.88 ± 0.12 0.03 ± 0.00
Pro-2 (WTproB*∆putA) 0.25 ± 0.00 17.20 ± 0.46 4.72 ± 0.07 1.36 ± 0.28 7.54 ± 0.23 1.47 ± 0.20 7.44 ± 0.82 1.69 ± 0.10 0.05 ± 0.00
Pro-3 (WTproB*P pck ::P acn acn*∆putA) 0.26 ± 0.00 16.45 ± 0.13 4.54 ± 0.11 1.36 ± 0.37 5.48 ± 0.32 1.82 ± 0.29 7.25 ± 0.91 1.79 ± 0.02 0.05 ± 0.00
Pro-4 (WTproB*P glyA ::P acn acn*∆putA) 0.25 ± 0.00 16.27 ± 0.12 4.42 ± 0.04 1.30 ± 0.50 4.98 ± 0.16 2.05 ± 0.32 7.33 ± 0.86 2.01 ± 0.07 0.06 ± 0.00
Pro-5 (WTproB*P eftu ::P acn acn*∆putA) 0.23 ± 0.00 15.94 ± 0.10 3.92 ± 0.10 1.25 ± 0.10 2.01 ± 0.28 2.56 ± 0.09 8.19 ± 0.57 2.26 ± 0.03 0.07 ± 0.00
Pro-6 (WTproB*P eftu ::P acn acn*∆putA/pXMJ19-proB*) 0.20 ± 0.00 14.65 ± 0.07 2.12 ± 0.13 0.72 ± 0.05 1.63 ± 0.27 0.37 ± 0.01 4.47 ± 0.85 18.71 ± 0.21 0.56 ± 0.00
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