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Table 2 Overview of l-proline-producing strains

From: A new genome-scale metabolic model of Corynebacterium glutamicum and its application

Strain Breeding Medium Titer (g/L) Yield (g/g) Productivity (g/L/h) References
Pro-6 Metabolic engineering Minimal medium 18.71 ± 0.21 0.36 ± 0.01 0.32 ± 0.01 This work
66.43b 0.26b 1.11b
Corynebacterium glutamicum Metabolic engineering Minimal medium   0.25–0.30a 0.25–0.30a [57]
Corynebacterium glutamicum Metabolic engineering Minimal medium 12.70 0.36 0.42 [56]
Corynebacterium acetoacidophilum l-Histidine auxotroph; mutation YPD medium 42b   1.66b [55]
Serratia marcescens SP511 Mutation Complete medium 100b   1.04ab [54]
  1. aEstimated from reference
  2. bAchieved in fed-batch fermentation
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