Fig. 6

Comparing empirical and in silico data in response to Δoah and Δgox knockouts. Markers represent empirical data and lines represent in silico data. Green circles and solid lines correspond to Δoah Δgox. Purple triangles and dashed-dotted lines correspond to Δoah. Brown squares and dashed lines correspond to Δgox. Blue diamonds and dotted lines correspond to ΔpyrG control. Empirical data plotted is the mean average of four biological replicates and error bars represent standard deviation. Citric acid data are normalised to reflect the amount produced. In silico data-points are one per minute. a Change in external citric acid concentration (g/L) over time. b Change in external oxalic acid concentration (g/L) over time. c Change in external gluconic acid concentration (g/L) over time. d Change in external phosphate concentration (g/L) over time