Table 2 Highly conserved tunnel-forming residues of GH48s
From: Natural diversity of glycoside hydrolase family 48 exoglucanases: insights from structure
B. pumilus | C. bescii | T. fusca | C. thermocellum | C. cellulolyticum |
|---|---|---|---|---|
His30 | His | His | His | His |
Glu38 | Glu | Glu | Glu | Glu |
Ala39 | Ala | Ala | Ala | Ala |
Glu49 | Glu | Glu | Glu | Glu |
Thr106 | Thr | Thr | Thr | Thr |
Ala108 | Ala | Ile | Ala | Ala |
Leu121 | Leu | Leu | Leu | Leu |
Trp150 | Trp | Trp | Trp | Trp |
Asn174 | Asn | Asn | Asn | Asn |
Phe176 | Phe | Tyr | Phe | Phe |
Gln177 | Gln | Gln | Gln | Gln |
Thr210 | Ile | Thr | Thr | Thr |
Glu212 | Asp | Asp | Asp | Asp |
Gln214 | Asn | Asn | Ser | Gly |
Gln219 | Gln | Gln | Gln | Gln |
Arg221 | Arg | Arg | Arg | Lys |
Thr223 | Thr | Thr | Thr | Thr |
Asp227 | Asp | Asp | Asp | Asp |
Lys267 | Lys | Lys | Lys | Lys |
Tyr268 | Tyr | Tyr | Tyr | Tyr |
Trp295 | Trp | Trp | Trp | Trp |
Tyr296 | Tyr | Tyr | Tyr | Tyr |
Ser298 | Ala | Ser | Ala | Ala |
Trp309 | Trp | Trp | Trp | Trp |
Trp311 | Trp | Trp | Trp | Trp |
Ile313 | Ile | Ile | Ile | Ile |
Tyr322 | Tyr | Tyr | Tyr | Tyr |
Tyr403 | Tyr | Trp | Tyr | Tyr |
Trp411 | Trp | Trp | Trp | Trp |
Met414 | Phe | Phe | Phe | Met |
Trp417 | Trp | Trp | Trp | Trp |
Asp534 | Asp | Asp | Asp | Asp |
Glu590 | Glu | Glu | Glu | Glu |
Arg592 | Arg | Pro | Arg | Arg |
Arg682 | Arg | Arg | Arg | Arg |
Trp684 | Trp | Trp | Trp | Trp |