Fig. 3
From: Metabolic engineering of Pichia pastoris for production of isobutanol and isobutyl acetate
The upper portion of l-valine biosynthesis from pyruvate to 2-ketoisovalerate. Ilv2, acetolactate synthase; Ilv5, acetohydroxyacid reductoisomerase; and Ilv3, dihydroxyacid dehydratase. In S. cerevisiae, acetolactate synthase is encoded by one gene, ScIlv2, while in P. pastoris, the enzyme is encoded by two genes, PpIlv2 and PpIlv6 (small or regulatory subunit of acetolactate synthase)