Fig. 1

Growth of different strains in xylose or a mixture of glucose and xylose. Bar plot representation of the growth rate (a) and the lag phase (b) of different Y. lipolytica strains. The absence of a bar means that no growth was detected. The values represent the average growth rate (1/h) or lag phase (h) and the standard deviation of at least two replicates growing in microplates. The strain named Po1d is a prototroph-derived strain. Minimal media was used with xylose as a carbon source, unless the carbon source is specified in the figure as glucose. Behavior of the strains ylXYL+ (c) and ylXYL+Obese (d) growing in a mixture of glucose and xylose. The graphics show the consumption of substrates (xylose and glucose, g/L), DCW (g/L), and production of metabolites (xylitol-XOH and citric acid-CA, g/L)