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Table 5 Comparison of 2,3-BD production in various microorganisms

From: Production of (2R, 3R)-2,3-butanediol using engineered Pichia pastoris: strain construction, characterization and fermentation

Species

Titer (g/L)

Operation strategy

Enantiopurity (%)

Yield (g/g)

Feed stock

2,3-BD productivity (g/L/h)

References

S. cerevisiae

43.6

Fed-batch

97

0.27

Xylose

0.15

[12]

S. cerevisiae

96.2

Fed-batch

NA

0.28

Glucose

0.39

[11]

S. cerevisiae

154.3

Fed-batch

NA

0.404

Glucose

1.97

[35]

S. cerevisiae

100

Fed-batch

98

0.35

Glucose and galactose

0.33

[14]

E. coli

6.9

Shake flask

99

0.31

Glucose

0.14

[36]

E. coli

73.8

Fed-batch

NA

0.41

Glucose

1.19

[30]

E. coli

115

Fed-batch

99

0.42

Glucose

1.44

[9]

E. aerogenes

152

Fed-batch

97.5

0.489

Glucose and xylose

3.5

[37]

E. aerogenes

140

Fed-batch

NA

NA

Sugarcane molasses

2.59

[38]

B. subtilis

49.29

Shake flask

99

0.47

Glucose

0.224

[4]

B. subtilis

130.7

Fed-batch

99

0.487

Glucose

0.459

[39]

B. licheniformis

123.7

Fed-batch

99

NA

Glucose

2.95

[6]

B. amyloliquefaciens

132.9

Fed-batch

NA

0.45

Glucose

2.95

[40]

K. oxytoca

131.5

Fed-batch

NA

0.44

Crude glycerol

0.84

[41]

K. oxytoca

117.4

Fed-batch

NA

0.49

Glucose

1.2

[42]

K. pneumoniae

150

Fed-batch

NA

NA

Glucose

4.21

[43]

S. marcescens

152

Fed-batch

NA

0.463

Sucrose

2.67

[44]

P. polymyxa

36.92

Batch

98

 

Raw inulin extract

0.88

[8]

C. glutamicum

6.3

Batch

NA

0.33

Glucose

0.2

[45]

Z. mobilis

15

Batch

NA

0.16

Glucose, xylose

0.3

[46]

P. pastoris

75

Fed-batch

99

0.3

Glucose

0.81

This study