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Table 2 Comparison of the crucial metabolic pathways among the five representative Clostridial strains
| Functional pathways (meta pathways labels) | Clostridial strains | ||||
|---|---|---|---|---|---|
| WA | BC1 | WB | DSM 15410 | NCIMB 14988 | |
| Carbohydrate metabolism | |||||
| Beta-1,4-d-mannosyl-N-acetyl-d-glucosamine degradation (PWY-7586) | Y | ||||
| Cellulose biosynthesis (PWY-1001) | Y | Y | |||
| Cellulose degradation II (PWY-6788) | Y | Y | Y | Y | Y |
| d-Galactose degradation V (Leloir pathway, PWY66-422) | Y | Y | Y | Y | |
| d-Galacturonate degradation I (GALACTUROCAT-PWY) | Y | Y | |||
| Ethanol degradation IV (PWY66-162) | Y | Y | Y | Y | |
| Fucose degradation (FUCCAT-PWY) | Y | ||||
| GDP-mannose biosynthesis (PWY-5659) | Y | ||||
| Gellan degradation (PWY-6827) | Y | ||||
| Gluconeogenesis I (GLUCONEO-PWY) | Y | Y | Y | ||
| Glycerol degradation I (PWY-4261) | Y | Y | Y | Y | Y |
| Glycogen biosynthesis I (GLYCOGENSYNTH-PWY) | Y | Y | |||
| Glycolysis I (GLYCOLYSIS) | Y | Y | Y | Y | Y |
| Glycolysis III (ANAGLYCOLYSIS-PWY) | Y | Y | Y | ||
| Lactose degradation III (BGALACT-PWY) | Y | ||||
| l-Ascorbate degradation II (PWY-6961) | Y | ||||
| l-Rhamnose degradation I (RHAMCAT-PWY) | Y | ||||
| Maltose degradation (MALTOSECAT-PWY) | Y | Y | |||
| Pentose phosphate pathway (NONOXIPENT-PWY) | Y | Y | |||
| Pyruvate fermentation to acetone (PWY-6588) | Y | Y | Y | Y | Y |
| Pyruvate fermentation to butanoate (CENTFERM-PWY) | Y | ||||
| Sucrose biosynthesis II (PWY-7238) | Y | Y | Y | Y | Y |
| Sucrose degradation III (PWY-621) | Y | Y | |||
| TCA cycle VIII (REDCITCYC) | Y | Y | Y | ||
| Trehalose degradation I (TREDEGLOW-PWY) | Y | ||||
| UDP-d-galactose biosynthesis (PWY-7344) | Y | Y | Y | Y | Y |
| UDP-glucose biosynthesis (PWY-7343) | Y | Y | Y | Y | Y |
| Energy metabolism | |||||
| [2Fe-2S] iron-sulfur cluster biosynthesis (PWY-7250) | Y | Y | Y | Y | Y |
| Hydrogen production (PWY-6759) | Y | Y | Y | Y | Y |
| Hydrogen to dimethyl sulfoxide electron transfer (PWY0-1577) | Y | Y | Y | Y | Y |
| Phosphatidylethanolamine biosynthesis I (PWY-5669) | Y | Y | Y | Y | |
| Sulfoquinovosyl diacylglycerol biosynthesis (PWYQT-4427) | Y | ||||
| Nitrogen fixation I (N2FIX-PWY) | Y | Y | Y | Y | |
| Superoxide radicals degradation (DETOX1-PWY) | Y | ||||
| Thioredoxin pathway (THIOREDOX-PWY) | Y | ||||
| Urate biosynthesis/inosine 5-phosphate degradation (PWY-5695) | Y | ||||
| Metabolism of cofactors, vitamins and others | |||||
| Acetate conversion to acetyl-CoA (PWY0-1313) | Y | ||||
| Acetate formation from acetyl-CoA I (PWY0-1312) | Y | Y | Y | Y | Y |
| Acyl-CoA hydrolysis (PWY-5148) | Y | ||||
| Phosphopantothenate biosynthesis I (PANTO-PWY) | Y | Y | Y | Y | Y |
| Riboflavin metabolism (RIBOFLAVIN-PWY) | Y | Y | Y | Y | Y |
| Fatty acid biosynthesis initiation I (PWY-4381) | Y | Y | |||
| CDP-diacylglycerol biosynthesis III (PWY-5981) | Y | Y | Y | ||
| Poly-hydroxy fatty acids biosynthesis (PWY-6710) | Y | Y | Y | Y | Y |
| 2,3-Dihydroxybenzoate biosynthesis (PWY-5901) | Y | Y | |||
