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Table 5 Production of succinate from non-food lignocellulosic biomass

From: Metabolic engineering of Corynebacterium glutamicum for efficient production of succinate from lignocellulosic hydrolysate

Strain Substrate (treatment) Conditions Titer (g/L) Yield (g/g) Productivity (g L−1 h−1) References
Actinobacillus succinogenes
 CGMCC1593 Corn straw (enzymatic hydrolysis) One stage, anaerobic fed-batch fermentation, complex medium 53.2 0.83 1.21 [48]
 CGMCC1593 Corn stover (enzymatic hydrolysis) One stage, anaerobic batch fermentation, complex medium 47.4 0.72a 0.99 [49]
 NJ113 Corn fiber (dilute acid hydrolysis) One stage, anaerobic batch fermentation, complex medium 35.4 0.73 0.98 [50]
 NJ113 Sugarcane bagasse (dilute acid hydrolysis) One stage, anaerobic batch fermentation, complex medium 23.7 0.79 0.99 [51]
 NJ113 Corn fiber hydrolysate (dilute acid hydrolysis) One stage, anaerobic batch fermentation, complex medium 47.6 0.68 0.63 [9]
 NJ113 Corn stover (enzymatic hydrolysis) One stage, anaerobic batch fermentation, complex medium 56.4 0.73 1.08 [52]
 130Z Corn stover (dilute acid hydrolysis, deacetylation) One stage, anaerobic continuous fermentation, complex medium 39.6 0.78 1.77 [53]
 130Z Corn stover (dilute acid hydrolysis, deacetylation) One stage, anaerobic batch fermentation, complex medium 42.8 0.74 1.27 [54]
 130Z Pinewood (enzymatic hydrolysis) One stage, anaerobic batch fermentation, complex medium 20.7 0.65 0.90 [55]
 CIP 106512 Sugarcane bagasse hemicellulose (dilute acid hydrolysis) One stage, anaerobic batch fermentation, complex medium 22.5 0.43 1.01 [56]
Escherichia coli
 BA204 Corn stalk (dilute acid hydrolysis) Two stages, aerobic culture of biomass and anaerobic batch fermentation, complex medium 11.1 1.02 0.70 [7]
 AFP 184 Spruce softwood (dilute acid hydrolysis) Two stages, aerobic culture of biomass and anaerobic batch fermentation, complex medium 42.2 0.72 0.78 [57]
 SD121 Corn stalk (enzymatic hydrolysis) Two stages, aerobic culture of biomass and anaerobic batch fermentation, complex medium 57.8 0.87 0.96 [8]
 BA305 Sugarcane bagasse (enzymatic hydrolysis) Two-stages, aerobic culture of biomass and anaerobic batch fermentation, Cell-recycling repeated fermentation, minimal medium 83b 0.87 2.31 [10]
 BA305 Sugarcane bagasse (not mentioned) One stage, anaerobic fed-batch fermentation, complex medium 39.3 0.97 0.33 [58]
 DC1515 Corn stalk (enzymatic hydrolysis) One stage, anaerobic batch fermentation, complex medium 38.6 0.39 0.80 [59]
Anaerobiospirillum succiniciproducens Oak wood (enzymatic hydrolysis) One stage, anaerobic batch fermentation, complex medium 24 0.88 0.75 [60]
Mannheimia succiniciproducens Oak wood (enzymatic hydrolysis) One stage, anaerobic batch fermentation, complex medium 11.7 0.56 1.17 [61]
Basfia succiniciproducens Corn stover (dilute acid hydrolysis) One stage, anaerobic batch fermentation, complex medium 30 0.69 0.43 [62]
Corynebacterium crenatum Wheat bran (dilute acid hydrolysis) Two stages, aerobic culture of biomass and anaerobic batch fermentation, Cell-recycling repeated fermentation, minimal medium 43.6 0.59 4.36 [63]
Corynebacterium glutamicum
 NC-2 Corn Cob (dilute acid hydrolysis) Two-stage, aerobic culture of biomass and anaerobic batch fermentation, minimal medium 40.8 0.69 0.85 [18]
 CGS5 Corn stalk (enzymatic hydrolysis) Two-stage, aerobic culture of biomass and anaerobic batch fermentation, minimal medium 98.6 0.87c 4.29 This study
  1. aThis yield was defined as the amount of succinic acid produced per substrate consumed
  2. bThe titer of 83 g L−1 was calculated by summing up the titers of three repetitive fermentations
  3. cThis yield was calculated based on the consumed glucose, xylose, and citrate