Fig. 7
Predicted fatty acid/lipid pathways in M. elongata AG77. Proteins likely involved in the synthesis of fatty acids (FA), polyunsaturated fatty acids (PUFA), and triacylglycerol (TAG) are identified in the sequenced genome of M. elongata AG77 at the JGI fungal genome portal MycoCosm (Additional file 8: Table S2). a FA synthesis. ACP, acyl carrier protein; AT, acetyltransferase; MPT, malonyl/palmitoyl transferase; ACSL, acyl-CoA synthetase; KS, β-ketoacyl synthase; ER, β-enoyl reductase; DH, dehydratase; KR, β-ketoacyl reductase. b Linear domain organization of fatty acid synthase (FASN) of M. elongata AG77. PPT, phosphopantetheine transferase. c PUFA synthesis. ELOVL, fatty acid elongase; FAD, fatty acid desaturase. Fatty acids are designated by the number of total carbon: the number of double bonds. The position of specific double bonds is indicated either from the carboxyl end (∆) or from the methyl end (ω). d TAG synthesis. ALDH, aldehyde dehydrogenase; ADH, alcohol dehydrogenase; GK, glycerol kinase; GPDH, glycerol-3-phosphate dehydrogenase; GPAT, glycero-3-phosphate acyltransferase; PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase; LPIN, phosphatidate phosphatase LPIN; PAP, phosphatidate phosphatase 2; Dgk, diacylglycerol kinase; DGAT, diacylglycerol acyltransferase; PDAT, phospholipid diacylglycerol acyltransferase