Fig.Ā 5From: Iterative cycle of widely targeted metabolic profiling for the improvement of 1-butanol titer and productivity in Synechococcus elongatusa PCA score plot and loading plot derived from DC7 and DC11. The score plot showed distinct separation of DC7 and DC11, represented by respective blue and purple circles. b The loading plot revealed CoA-dependent pathway-related metabolites, amino acids, and sugars had a positive contribution for separating DC11 with DC7. c Relative intensity of intracellular butanoyl-CoA, malonyl-CoA, acetyl-CoA and (iso-) citrate in DC7 and DC11. Asterisks indicate significant differences in the strains (*pāā¤ā0.05; **pāā¤ā0.01). d RT-PCR for heterologous accase expressed in S. elongatus PCC7942Back to article page